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Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension

CHEN Jisheng, HUO Jinshan, ZHANG Hongwei, SHANG Changzhen, CHEN Rufu, ZHANG Jie, Obetien Mapudengo, CHEN Yajin, ZHANG Lei

《医学前沿(英文)》 2007年 第1卷 第1期   页码 30-35 doi: 10.1007/s11684-007-0006-6

摘要: The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated. In this study, we evaluated the effectiveness of a new treatment strategy: splenic auto-transplantation and oesophageal transection anastomosis on 274 patients from three aspects: clinical observation, splenic immunology and portal dynamics. From 1979 to 2005, 274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes, which were then compared with those of the traditional surgery treatment. From 1999 to 2002, a randomized control trial (RCT) was performed on 40 patients to compare their immune function after operation. From 1994 to 2004, another RCT was carried out on 28 patients to compare the portal dynamics through three-dimensional dynamic contrast enhanced MR angiography (3D DEC MRA) investigation after operation. Among 274 patients (mean age 41.8 years), the emergency operative mortality (4.4%), selective operative mortality (2.2%), complication rate (17.9%), morbidity of hepatic encephalopathy (<1%), bleeding rate of portal hypertension gastritis (PHG) (9.1%), and morbidity of hepatic carcinoma (8%) were similar to those under traditional operation; the spleen immunology function (Tuftsin, IgM) decreased among the groups 2 months after operation. Through 3D DCE MRA, the cross section area, the velocity and volume of blood flow of main portal vein decrease significantly after operation in both groups, the auto transplantation group was significantly lower in velocity and volume of blood flow than in the control group. Splenic auto transplantation and esophageal transection anastomosis are a safe, effective, and reasonable treatment strategy for portal hypertension with varicial bleeding. It can not only correct hypersplenism but also completely stanch blood, and auto transplanted spleen in the retroperitoneal space can preserve immune function and establish abroad collateral circulation.

关键词: esophageal transection     oesophageal transection     RCT     dynamic contrast     DCE MRA    

Urotensin II receptor antagonist reduces hepatic resistance and portal pressure through enhanced eNOS-dependent

Ruoxi Zhang, Jing Chen, Diangang Liu, Yu Wang

《医学前沿(英文)》 2019年 第13卷 第3期   页码 398-408 doi: 10.1007/s11684-019-0689-5

摘要: Increased serum urotensin II (UII) levels in human cirrhotic populations have been recently shown, but the long-term effects of UII receptor antagonist on the cirrhosis have not been investigated. To investigate the therapeutic effects of urotensin II receptor (UT) antagonist palosuran on rats with carbon tetrachloride (CCl )-induced cirrhosis, the hepatic and systemic hemodynamics, liver fibrosis, the metalloproteinase-13 (MMP-13)/ tissue inhibitor of metalloproteinase-1 (TIMP-1) ratio, hepatic Rho-kinase activity, and the endothelial nitric oxide synthase (eNOS) activity are measured in CCl -cirrhotic rats treated with palosuran or vehicle for 4 weeks. Primary hepatic stellate cells (HSCs) are used to investigate the changes in UII/UT expression and the effect of palosuran. Compared with the vehicle-treated cirrhotic rats, treatment with palosuran can reduce the portal pressure (PP), decrease the risk of liver fibrosis and the level of α smooth muscle actin, collagen-I (COL-I), and transforming growth factor β expression. However, treatment with palosuran can increase MMP-13/TIMP-1, p-vasodilator-stimulated phosphoprotein (p-VASP), and p-eNOS expression. Moreover, UII/UT mRNA expression increases during HSC activation. MMP-13/TIMP-1, COL-I, and p-VASP are inhibited after palosuran treatment. Our data indicate that long-term administration of palosuran can decrease PP in cirrhosis, which results from decreased hepatic fibrosis and enhanced eNOS-dependent HSC vasodilatation.

关键词: portal hypertension     cirrhosis     urotensin II     palosuran     hepatic stellate cell    

Effects of combined procedure and devascularization alone on hyperdynamics of the portal venous systemin patients with portal hypertension

HUA Rong, SUN Yongwei, WU Zhiyong

《医学前沿(英文)》 2008年 第2卷 第3期   页码 244-247 doi: 10.1007/s11684-008-0046-6

摘要: Shunts and devascularizations have totally different effects on the hemodynamics of the portal venous system. The actual results of pericardial devascularization (PCDV) alone and conventional splenorenal shunt combined with pericardial devascularization (combined procedure, CP) should be determined by more clinical observations. This study aimed to evaluate effects on hemodynamics in the portal venous system after CP and PCDV only. In 20 patients who received CP and 18 who received PCDV, hemodynamic parameters of the portal venous system were studied by magnetic resonance angiography 1 week before and 2 weeks after operation. Free portal pressure (FPP) was continuously detected by a transducer during the operations. Compared to the preoperative data, a decreased flow in the portal vein (PVF) [(563.12 ± 206.42) mL/min (1080.63 ± 352.85) mL/min, < 0.05], a decreased portal vein diameter (PVD) [(1.20 ± 0.11) cm (1.30 ± 0.16) cm, < 0.01], a decreased FPP [(21.50 ± 2.67) mmHg (29.88 ± 2.30) mmHg, < 0.01] and an increased flow in the superior mesenteric vein (SMVF) [(1105.45 ± 309.03) mL/min (569.13 ± 178.46) mL/min, < 0.05] were found in the CP group after operation; a decreased PVD [(1.27 ± 0.16) cm (1.40 ± 0.23) cm, < 0.05], a decreased PVF [(684.60 ± 165.73) mL/min (1175.64 ± 415.09) mL/min, < 0.05], a decreased FPP [(24.40 ± 3.78) mmHg (28.80 ± 3.56) mmHg, < 0.05] and an increased SMVF [(697.91 ± 121.83) mL/min (521.30 ± 115.82) mL/min, < 0.05] were observed in the PCDV group. After operation, PVF in the CP group [(563.12 ± 206.42) mL/min (684.60 ± 165.73) mL/min, > 0.05] had no significant decrease, while FPP [(21.50 ± 2.67) mmHg (24.40 ± 3.78) mmHg, < 0.01] had a significant decrease as compared with that in the PCDV group. PVF and FPP could be decreased by both surgical procedures, but the effect of decreasing FPP was much better in the combined procedure than in PCDV alone. Further, there was no significant difference in PVF between the two groups. It is suggested that the combined surgical procedure could integrate the advantages of shunting with those of devascularization, as well as maintaining the normal anatomic structure of hepatic portal system, thus it should be one of the best choices for patients with portal hypertension when surgical interventions are considered.

J-shaped association between dietary zinc intake and new-onset hypertension: a nationwide cohort study

《医学前沿(英文)》 2023年 第17卷 第1期   页码 156-164 doi: 10.1007/s11684-022-0932-3

摘要: We aimed to investigate the relationship of dietary zinc intake with new-onset hypertension among Chinese adults. A total of 12,177 participants who were free of hypertension at baseline from the China Health and Nutrition Survey were included. Dietary intake was assessed by three consecutive 24-h dietary recalls combined with a household food inventory. Participants with systolic blood pressure 140 mmHg or diastolic blood pressure 90 mmHg or diagnosed by a physician or under antihypertensive treatment during the follow-up were defined as having new-onset hypertension. During a median follow-up duration of 6.1 years, 4269 participants developed new-onset hypertension. Overall, the association between dietary zinc intake and new-onset hypertension followed a J-shape (P for non-linearity < 0.001). The risk of new-onset hypertension significantly decreased with the increment of dietary zinc intake (per mg/day: hazard ratio (HR) 0.93; 95% confidence interval (CI) 0.88–0.98) in participants with zinc intake < 10.9 mg/day, and increased with the increment of zinc intake (per mg/day: HR 1.14; 95% CI 1.11–1.16) in participants with zinc intake 10.9 mg/day. In conclusion, there was a J-shaped association between dietary zinc intake and new-onset hypertension in general Chinese adults, with an inflection point at about 10.9 mg/day.

关键词: dietary zinc intake     new-onset hypertension     general population     CHNS    

Metabolic hypertension: concept and practice

null

《医学前沿(英文)》 2013年 第7卷 第2期   页码 201-206 doi: 10.1007/s11684-013-0264-4

摘要:

Hypertension is a serious public health problem worldwide. More than 60% of the risk factors for hypertension are associated with metabolic disturbances. Metabolic abnormalities increase the risk for hypertension and cause high blood pressure. Improving metabolic disturbances is beneficial for hypertension treatment. Due to the importance of metabolic abnormalities in the pathogenesis of hypertension, we propose a concept of metabolic hypertension. In this review, we discuss and review the clinical types, pathogenesis, risk evaluation and management of metabolic hypertension. Elucidation of the mechanism of metabolic hypertension should facilitate the design of novel pharmacotherapeutics and dedicated antihypertensive manipulations.

关键词: hypertension     cardiometabolic risk factors     metabolic abnormalities    

Optimal design of steel portal frames based on genetic algorithms

CHEN Yue, HU Kai

《结构与土木工程前沿(英文)》 2008年 第2卷 第4期   页码 318-322 doi: 10.1007/s11709-008-0055-1

摘要: As for the optimal design of steel portal frames, due to both the complexity of cross selections of beams and columns and the discreteness of design variables, it is difficult to obtain satisfactory results by traditional optimization. Based on a set of constraints of the Technical Specification for Light-weighted Steel Portal Frames of China, a genetic algorithm (GA) optimization program for portal frames, written in MATLAB code, was proposed in this paper. The graph user interface (GUI) is also developed for this optimal program, so that it can be used much more conveniently. Finally, some examples illustrate the effectiveness and efficiency of the genetic-algorithm-based optimal program.

关键词: satisfactory     genetic-algorithm-based     Technical Specification     algorithm     efficiency    

Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive

null

《医学前沿(英文)》 2013年 第7卷 第3期   页码 395-395 doi: 10.1007/s11684-013-0289-8

A modified chronic ocular hypertension rat model for retinal ganglion cell neuroprotection

null

《医学前沿(英文)》 2013年 第7卷 第3期   页码 367-377 doi: 10.1007/s11684-013-0266-2

摘要:

This study aimed to modify a chronic ocular hypertension (OHT) rat model to screen for potential compounds to protect retinal ganglion cells (RGCs) from responding to increased intraocular pressure (IOP). A total of 266 rats were prepared and randomly grouped according to different time-points, namely, weeks 3, 8, 16, and 24. Rats were sedated and eye examination was performed to score as the corneal damage on a scale of 1 to 4. The OHT rat model was created via the injection of a hypertonic saline solution into the episcleral veins once weekly for two weeks. OHT was identified when the IOP at week 0 was≥6 mmHg than that at week -2 for the same eye. Viable RGCs were labeled by injecting 4% FluoroGold. Rats were sacrificed, and the eyes were enucleated and fixed. The fixed retinas were dissected to prepare flat whole-mounts. The viable RGCs were visualized and imaged. The IOP (meanβ±βSD) was calculated, and data were analyzed by the paired t-test and one-way ANOVA. The OHT model was created in 234 of 266 rats (87.97%), whereas 32 rats (12.03%) were removed from the study because of the absence of IOP elevation (11.28%) and/or corneal damage scores over 4 (0.75%). IOP was elevated by as much as 81.35% for 24 weeks. The average IOP was (16.68β±β0.98)βmmHg in non-OHT eyes (n = 234), but was (27.95±0.97)βmmHg in OHT eyes (n = 234). Viable RGCs in the OHT eyes were significantly decreased in a time-dependent manner by 29.41%, 38.24%, 55.32%, and 59.30% at weeks 3, 8, 16, and 24, respectively, as compared to viable RGCs in the non-OHT eyes (P<β0.05). The OHT model was successfully created in 88% of the rats. The IOP in the OHT eyes was elevated by approximately 81% for 24 weeks. The number of viable RGCs was decreased by 59% of the rats in a time-dependent manner. The modified OHT model may provide an effective and reliable method for screening drugs to protect RGCs from glaucoma.

关键词: chronic ocular hypertension     intraocular pressure     retinal ganglion cells     neuroprotection     glaucoma    

Effectiveness of lifestyle intervention for hypertension in Shanghai communities: Results from the ShanghaiHypertension Detail Management Program

Xin-Jian LI MD, Min-Na CHENG MPH, Yu-Heng WANG MD, Sun MIAO MPH, Zong-Qi ZHANG PhD, Yi-Sheng CHEN MD, Wei LU PhD,

《医学前沿(英文)》 2010年 第4卷 第1期   页码 67-70 doi: 10.1007/s11684-010-0023-8

摘要: A community-based multi-center randomized controlled trial was conducted to evaluate the effectiveness of blood pressure control for hypertension patients in communities in urban Shanghai by integrated intervention. At present, patients (=1395) from four communities have completed follow-up for one year, including the intervention group (=921) and usual care group (=474). The intervention programs included disease management by a care manager. Blood pressure of each patient was measured regularly. Compared with the control group, the net change of mean systolic blood pressure (SBP) was −6.75 (95% CI: −7.79 to −5.71, <0.001) mmHg, mean diastolic blood pressure (DBP) was −4.29 (95% CI: −5.08 to −3.49, <0.001) mmHg, and mean pulse pressure (PP) was −2.46 (95% CI: −3.50 to −1.43, <0.001) mmHg in the intervention group. The net change extent was larger in patients with regular pharmacological treatment than in those with irregular pharmacological treatment or non-pharmacological treatment. The measures of integrated intervention for hypertension patients in communities can lower significantly not only SBP and DBP, but also PP. It is suggested that measures of integrated intervention can decrease the risk of cardiovascular diseases in hypertension patients.

关键词: hypertension     community     pharmacological adherence     control of blood pressure    

Temperature effects of shape memory alloys (SMAs) in damage control design of steel portal frames

Xiaoqun LUO, Hanbin GE, Tsutomu USAMI

《结构与土木工程前沿(英文)》 2012年 第6卷 第4期   页码 348-357 doi: 10.1007/s11709-012-0176-4

摘要: The objective of the present study is to analytically investigate temperature effects of an axial-type seismic damper made of shape memory alloys (SMAs) equipped in steel frames. Based on a modified multilinear one dimensional constitutive model of SMAs, two types of SMAs are employed, which have different stress plateau and different stress growth rate with temperature increase. Temperature effects of SMA dampers on seismic performance upgrading are discussed in three aspects: different environment temperatures; rapid loading rate induced heat generation and different SMA fractions. The analysis indicates that the effect of environment temperature should be considered for the SMA damper in steel frames. However, the rapid loading rate induced heat generation has little adverse effect.

关键词: damage control design     shape memory alloy     temperature effect    

Clinical characteristics of pulmonary hypertension in bronchiectasis

null

《医学前沿(英文)》 2016年 第10卷 第3期   页码 336-344 doi: 10.1007/s11684-016-0461-z

摘要:

Pulmonary hypertension (PH), as a complication of bronchiectasis, is associated with increased mortality. However, hemodynamic characteristics and the efficacy of pulmonary arterial hypertension (PAH) therapies in patients with bronchiectasis and PH remain unknown. Patients with bilateral bronchiectasis and concurrent PH were included in the study. Patient characteristics at baseline and during follow-up, as well as survival, were analyzed. This observational study was conducted in 36 patients with a mean age of 51.5 years (range, 17?74 years). The 6 min walking distance was 300.8±93.3 m. The mean pulmonary arterial pressure (PAP) was 41.5±11.7 mmHg, cardiac output was 5.2±1.4 L/min, and pulmonary vascular resistance was 561.5±281.5 dyn·s·cm5. The mean PAP was>35 mmHg in 75% of the cases. Mean PAP was inversely correlated with arterial oxygen saturation values (r = −0.45, P = 0.02). In 24 patients who received oral PAH therapy, systolic PAP was reduced from 82.4±27.0 mmHg to 65.5±20.9 mmHg (P = 0.025) on echocardiography after a median of 6 months of follow-up. The overall probability of survival was 97.1% at 1 year, 83.4% at 3 years, and 64.5% at 5 years. Given the results, we conclude that PH with severe hemodynamic impairment can occur in patients with bilateral bronchiectasis, and PAH therapy might improve hemodynamics in such patients. Prospective clinical trials focusing on this patient population are warranted.

关键词: bronchiectasis     hemodynamics     pulmonary hypertension    

Obesity and overweight prevalence and its association with undiagnosed hypertension in Shanghai population

null

《医学前沿(英文)》 2012年 第6卷 第3期   页码 322-328 doi: 10.1007/s11684-012-0204-8

摘要:

The aim of this study was to determine the prevalence of overweight and obese subjects in the Shanghai population of China and its association with undiagnosed hypertension, by taking age, gender and place of residence (urban or suburban) into account. A cross-sectional population-based survey was conducted in 2007. The sample included 13 359 participants aged 15–69 years. Weight, height, and blood pressure were recorded, and information about gender, age and place of residence was obtained. Overweight and obesity prevalence were calculated by the body mass index (BMI) definition recommended by Working Group on Obesity in China (normal weight, 18.5–23.9 kg/m2; overweight, 24–27.9 kg/m2; obesity,≥28 kg/m2). Undiagnosed hypertension was defined by China criteria in accord with that of WHO-ISH (subjects with systolic pressure≥140 mmHg, and/or diastolic pressure≥90 mmHg). Multiple logistic regression analyses were used to assess the association of overweight or obesity with undiagnosed hypertension by adjusting for age, gender and place of residence. The overall overweight, obesity, and undiagnosed hypertension prevalence were 27.6% (95% CI: 26.8–28.4), 6.6% (95% CI: 6.2–7.0), and 15.5% (95% CI: 14.9–16.1), respectively. Compared to normal weight subjects, the odds ratios (OR) for subjects who were overweight and had hypertension was 2.33 (95% CI: 2.10–2.59); that for obesity and hypertension was 4.27 (95% CI: 3.66–4.99). These data suggest that overweight and obesity prevalence and their association with undiagnosed hypertension are high in our study population.

关键词: overweight     obesity     undiagnosed hypertension     prevalence     association    

Improved control of hypertension following laparoscopic fundoplication for gastroesophageal reflux disease

null

《医学前沿(英文)》 2017年 第11卷 第1期   页码 68-73 doi: 10.1007/s11684-016-0490-7

摘要:

This study aims to determine whether successful laparoscopic fundoplication for gastroesophageal reflux disease (GERD) can improve the control of hypertension. We conducted an observational study of GERD patients with hypertension. The esophageal and gastroesophageal symptoms of these patients were successfully treated with laparoscopic fundoplication, as measured by the reduced GERD symptoms and proton pump inhibitor consumption. A hypertension control scale was used to classify the use of antihypertensive medications and the quality of blood pressure control before and after anti-reflux surgery. Wilcoxon signed-ranks test was used for the statistical analyses. Seventy GERD patients were included in the analysis and followed up for a mean period of 3.5±1.4 years. Prior to surgery, all participating patients were taking at least one class of antihypertensive medication, and 56 patients (80%) had intermittently high blood pressure. After surgery, the mean number of antihypertensive medication classes per patient was significantly reduced from 1.61±0.77 pre-procedure to 1.27±0.88 post-procedure (P?<?0.001). The blood pressure of 48 of the 56 cases (86%) with preoperative intermittent high blood pressure returned to normal post procedure. A total of 50 patients (71%) recorded improvements on the hypertension control scale, with the overall mean score decreasing from 3.1±1.0 pre-procedure to 1.4±1.0 post-procedure (P?<?0.001). Therefore, successful laparoscopic fundoplication may result in better blood pressure control in some hypertensive GERD patients. This result suggests a possible connection between gastroesophageal reflux and hypertension.

关键词: gastroesophageal reflux disease     hypertension     blood pressure     laparoscopic fundoplication    

Partial portacaval shunt with H-grafts to treat portal hypertension

XU Geliang, HU Hejie, LI Jiansheng, YANG Shugao, CHAI Zhongpei, XU Rongnan

《医学前沿(英文)》 2007年 第1卷 第3期   页码 279-281 doi: 10.1007/s11684-007-0053-z

摘要: Partial portosystemic shunts have been popularized because of a reported low rate of mortality and morbidity (especially encephalopathy, liver failure and occlusion). The results of partial portacaval shunts [small-diameter expanded polytetrafluoroethylene (ePTFE) H-graft portacaval shunt] were retrospectively reviewed to evaluate the clinical efficacy in the treatment of portal hypertension. Forty-three patients with portal hypertension were treated by small-diameter H-graft of ePTFE portacaval shunt from May 1995 to April 2006. Thirty-three had externally ringed grafts and ten had non-ringed ones. Ten had grafts of 10 mm in diameter and 33 had grafts of 8 mm. The left gastric artery and coronary vein were ligated in all the cases. Six had pericardial devascularization and splenectomy was performed in 42. An average decrease of free portal pressure (FPP) from (33.24 ± 4.78) cmHO before shunting and (13.65 ± 5.65) cmHO after shunting was observed. The portal blood flow was reduced by one-third of that before shunt. Thirty-eight patients survived and no upper gastro-intestinal rebleeding occurred in the follow-up period (50.5 months in average). Two were out of contact. Color Doppler ultrasonography and/or portography revealed the shunts were patent in 38 cases and were occluded in three cases (3/41, 7.3%). Encephalopathy developed in five cases (5/41, 12.2%). Partial (small-diameter ePTFE H-graft) portacaval shunting can reduce the portal pressure effectively. Majority of the hepatic flow from the portal vein can be maintained adequately. The shunts with reinforced grafts can keep a higher rate of patency. The morbidity of encephalopathy was lower than those with total shunt. The partial portacaval shunt is effective in preventing recurrent variceal bleeding.

关键词: diameter     clinical efficacy     bleeding     pericardial devascularization     Forty-three    

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

《医学前沿(英文)》 2007年 第1卷 第2期   页码 167-172 doi: 10.1007/s11684-007-0031-5

摘要: An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) after liver transplantation has not been established previously. The aim of this retrospective study was to understand the role of IAH as an independent risk factor for ARF in the early postoperative period. This study involved 62 subjects who underwent liver transplantation. Intra-abdominal pressure (IAP) was measured in the first three days after surgery by using the urinary bladder technique. An IAP of at least 20 mmHg per day was defined as IAH. Clinical parameters between group IAH and group NO-IAH were compared in terms of the incidence of ARF, blood creatinine levels, blood urea nitrogen (BUN) levels, urine volume per hour and glomerular filtration gradient (GFG). Hemodynamic variations were recorded in the first three postoperative days between group ARF and group NO-ARF. The perioperative suspected risk factors of ARF were determined for statistical evaluation using correlation coefficients and logistic regression analysis. In group IAH, 45.8% patients developed ARF as against 7.9% in group NO-IAH; GFG was significantly lower at 0 72 h after surgery; and blood creatinine levels, BUN levels, urine volume per hour were significantly different at 24 72 h after surgery compared with group NO-IAH. The patients with ARF were not significantly different from those without ARF in terms of central venous pressure, pulmonary artery pressure and mean arterial pressure (MAP) in the first three postoperative days despite a significant increase in heart rate at 24 72h after operation. Postoperative IAH, intraoperative MAP and intraoperative blood transfusion volume of more than 15 U were found to be independent risk factors for ARF. IAH impaired renal function and was an independent risk factor for ARF after liver transplantation. Routine measurement should be taken to monitor IAP every eight hours postoperatively.

标题 作者 时间 类型 操作

Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension

CHEN Jisheng, HUO Jinshan, ZHANG Hongwei, SHANG Changzhen, CHEN Rufu, ZHANG Jie, Obetien Mapudengo, CHEN Yajin, ZHANG Lei

期刊论文

Urotensin II receptor antagonist reduces hepatic resistance and portal pressure through enhanced eNOS-dependent

Ruoxi Zhang, Jing Chen, Diangang Liu, Yu Wang

期刊论文

Effects of combined procedure and devascularization alone on hyperdynamics of the portal venous systemin patients with portal hypertension

HUA Rong, SUN Yongwei, WU Zhiyong

期刊论文

J-shaped association between dietary zinc intake and new-onset hypertension: a nationwide cohort study

期刊论文

Metabolic hypertension: concept and practice

null

期刊论文

Optimal design of steel portal frames based on genetic algorithms

CHEN Yue, HU Kai

期刊论文

Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive

null

期刊论文

A modified chronic ocular hypertension rat model for retinal ganglion cell neuroprotection

null

期刊论文

Effectiveness of lifestyle intervention for hypertension in Shanghai communities: Results from the ShanghaiHypertension Detail Management Program

Xin-Jian LI MD, Min-Na CHENG MPH, Yu-Heng WANG MD, Sun MIAO MPH, Zong-Qi ZHANG PhD, Yi-Sheng CHEN MD, Wei LU PhD,

期刊论文

Temperature effects of shape memory alloys (SMAs) in damage control design of steel portal frames

Xiaoqun LUO, Hanbin GE, Tsutomu USAMI

期刊论文

Clinical characteristics of pulmonary hypertension in bronchiectasis

null

期刊论文

Obesity and overweight prevalence and its association with undiagnosed hypertension in Shanghai population

null

期刊论文

Improved control of hypertension following laparoscopic fundoplication for gastroesophageal reflux disease

null

期刊论文

Partial portacaval shunt with H-grafts to treat portal hypertension

XU Geliang, HU Hejie, LI Jiansheng, YANG Shugao, CHAI Zhongpei, XU Rongnan

期刊论文

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

期刊论文